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ea0034oc1.2 | Young Endocrinologists prize session | SFEBES2014

Characterisation of adrenocortical progenitor cells: isolation of mesenchymal stem cell-like cell populations from human adrenal cortex

Gan Earn , Robson Wendy , Lennard Thomas , Pearce Simon , Oldershaw Rachel

Background: The plasticity of adrenal cortex suggests the presence of adrenocortical stem cells (ACSC) but the exact in vivo identity of ACSC remains elusive. A few studies have demonstrated the differentiation of adipose or bone marrow-derived mesenchymal stem cells (MSC) into steroid-producing cells. We therefore investigated the direct isolation of MSC from human adrenal cortex.Methods: Adrenals were obtained as discarded surgical material. S...

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ea0038p43 | Clinical practice/governance and case reports | SFEBES2015

What is the prevalence of severe post-operative hypocalcaemia in patients who have undergone parathyroid surgery or a total thyroidectomy at the RVI, Newcastle? Does vitamin D play a role?

Pawlak Anna , Quinton Richard , Truran Peter , Lennard Thomas , Bliss Richard , Heed Andrew

Background: Hypocalcaemia is a common electrolyte disorder and it can occur following parathyroidectomy or thyroidectomy. It has been suggested that some post-operative hypocalcaemic crises may reflect severe vitamin D deficiency and vitamin D supplementation may have a protective effect.Objectives: To establish the prevalence of severe post-operative hypocalcaemia (as defined by the requirement for i.v. calcium gluconate) following parathyroid surgery a...

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Endocrine Abstracts

Characterisation of adrenocortical progenitor cells: isolation of mesenchymal stem cell-like cell populations from human adrenal cortex

What is the prevalence of severe post-operative hypocalcaemia in patients who have undergone parathyroid surgery or a total thyroidectomy at the RVI, Newcastle? Does vitamin D play a role?

BiosciAbstracts